⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180621 | 0.80 | TP53 (0.30) | — | |
| SCHEMBL16597718 | 0.75 | — | — | |
| SCHEMBL9319092 | 0.72 | TSHR (0.30) | — | |
| SCHEMBL9322637 | 0.71 | — | — | |
| SCHEMBL182639 | 0.70 | — | — | |
| SCHEMBL9322631 | 0.69 | — | — | |
| SCHEMBL11882765 | 0.69 | — | — | |
| SCHEMBL2302737 | 0.69 | — | — | |
| SCHEMBL28272165 | 0.67 | TP53 (0.42) | — | |
| SCHEMBL11011502 | 0.67 | TP53 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180002367-A1 | Phosphorodiamidate Backbone Linkage for Oligonucleotides | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2018-01-04 | — | — | US | claimed |
| WO-2023142803-A1 | ANTIVIRAL COMPOUND AND USE THEREOF | 北京恩泰伟医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| US-10905782-B2 | Compositions for enhancing transport of molecules into cells | SAREPTA THERAPEUTICS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| CN-110563757-A | Preparation method of amino-tri (dimethylamino) phosphonium chloride | 中国石油化工股份有限公司 | 2019-12-13 | — | — | CN | disclosed |
| US-10300149-B2 | Compositions for enhancing transport of molecules into cells | SAREPTA THERAPEUTICS, INC. (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180002367-A1 | Phosphorodiamidate Backbone Linkage for Oligonucleotides | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2018-01-04 | — | — | US | disclosed |
| US-20170368203-A1 | Compositions For Enhancing Transport Of Molecules Into Cells | SAREPTA THERAPEUTICS, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9708360-B2 | Phosphorodiamidate backbone linkage for oligonucleotides | GERON CORPORATION (US) | 2017-07-18 | — | — | US | disclosed |
| US-9572899-B2 | Compositions for enhancing transport of molecules into cells | AVI BIOPHARMA, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3052512-A1 | PHOSPHORODIAMIDATE BACKBONE LINKAGE FOR OLIGONUCLEOTIDES | Geron Corporation (US) | 2016-08-10 | — | — | EP | disclosed |
| US-5378841-A | Alpha-morpholino ribonucleoside derivatives and polymers thereof | ANTIVIRALS INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1994012517-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0592511-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS. | ANTIVIRALS INC (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5235033-A | ALPHA-MORPHOLINO RIBONUCLEOSIDE DERIVATIVES AND POLYMERS THEREOF | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-08-10 | — | — | US | disclosed |
| US-5185444-A | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages | ANTI-GENE DEVEOPMENT GROUP (US) | 1993-02-09 | — | — | US | disclosed |
| WO-1993000352-A1 | SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS | ANTIVIRALS INC. (US) | 1993-01-07 | — | — | WO | disclosed |
| EP-0506830-A4 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES | — | 1993-01-07 | — | — | EP | disclosed |
| US-5166315-A | Polynucleotides for genetic engineering | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0506830-A1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES | ANTIVIRALS INC. (US) | 1992-10-07 | — | — | EP | disclosed |
| WO-1991009033-A1 | UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES | ANTI-GENE DEVELOPMENT GROUP (US) | 1991-06-27 | — | — | WO | disclosed |