SCHEMBL180621

SCHEMBL180621

CN(C)OP(=O)(Cl)ON(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2302735 0.80
SCHEMBL16597718 0.75
SCHEMBL9319092 0.72 TSHR (0.30)
SCHEMBL9322631 0.69
SCHEMBL2302737 0.69
SCHEMBL11882765 0.69
SCHEMBL9559490 0.67
SCHEMBL9839912 0.67 TP53 (0.38) TP53TDP1
SCHEMBL6233076 0.67
SCHEMBL18585214 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528974-A Preparation method of beta-sodium glycerophosphate 合肥市未来药物开发有限公司 2025-02-28 CN claimed
CN-118307587-A 4-Nitrophenyl disodium phosphate and preparation method thereof 苏州昊帆生物股份有限公司 2024-07-09 CN claimed
CN-117757247-A Linear phosphonamide oligomer flame retardant synergistic flame retardant thermoplastic polyurethane elastomer composite material and preparation method thereof 北京工商大学 2024-03-26 CN claimed
CN-117757084-A Linear phosphonamide oligomer flame retardant, preparation method thereof and application thereof in thermoplastic polyurethane elastomer 北京工商大学 2024-03-26 CN claimed
CN-116812915-B Nitrogen-nickel-copper doped carbon material and preparation method and application thereof 河北省科学院能源研究所 2024-03-19 CN claimed
CN-117089061-A Flame-retardant polyester polyol and preparation method and application thereof 万华化学集团股份有限公司 2023-11-21 CN claimed
CN-113512452-B Diesel engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-114082309-B Polyphosphazene amide nanofiltration membrane with high-valence charge group on surface and preparation method thereof 北京碧水源膜科技有限公司 2023-10-10 CN claimed
CN-113512451-B Lubricating oil composition for internal combustion engine and preparation method thereof 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-111057101-B Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN claimed
CN-116812915-A Nitrogen-nickel-copper doped carbon material and preparation method and application thereof 河北省科学院能源研究所 2023-09-29 CN claimed
CN-111057108-B Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2023-08-15 CN claimed
CN-114874456-B Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2023-03-03 CN claimed
CN-114874456-A Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2022-08-09 CN claimed
CN-114082309-A Poly-phosphorus based amide nanofiltration membrane with high-valence charge groups on surface and preparation method thereof 北京碧水源膜科技有限公司 2022-02-25 CN claimed
CN-113549484-A Acid-washing-free drawing coating powder for steel wire and preparation method thereof 南京华舜润滑制品有限公司 2021-10-26 CN claimed
CN-113004963-A Antirust high-lubricity cutting fluid and preparation process thereof 安徽联亚新材料有限公司 2021-06-22 CN claimed
CN-112961724-A Extreme pressure antiwear agent and preparation method thereof 上海中器实业有限公司 2021-06-15 CN claimed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US claimed
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2026-04-07 US disclosed
CN-119930689-A Synthetic method of bio-based phosphorus-nitrogen synergistic flame retardant and high-flame-retardance polymer composition prepared by using same 浙江嘉民新材料有限公司 2025-05-06 CN disclosed
CN-119528974-A Preparation method of beta-sodium glycerophosphate 合肥市未来药物开发有限公司 2025-02-28 CN disclosed
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-01-30 US disclosed
CN-118307587-A 4-Nitrophenyl disodium phosphate and preparation method thereof 苏州昊帆生物股份有限公司 2024-07-09 CN disclosed
CN-118307587-A 4-Nitrophenyl disodium phosphate and preparation method thereof 苏州昊帆生物股份有限公司 2024-07-09 CN disclosed
CN-111607038-B Resin composition and product 洛阳尖端技术研究院 2024-05-07 CN disclosed
CN-117936908-A Lithium metal battery electrolyte and preparation method thereof 华南理工大学 2024-04-26 CN disclosed
CN-117757247-A Linear phosphonamide oligomer flame retardant synergistic flame retardant thermoplastic polyurethane elastomer composite material and preparation method thereof 北京工商大学 2024-03-26 CN disclosed
CN-117757084-A Linear phosphonamide oligomer flame retardant, preparation method thereof and application thereof in thermoplastic polyurethane elastomer 北京工商大学 2024-03-26 CN disclosed
CN-116812915-B Nitrogen-nickel-copper doped carbon material and preparation method and application thereof 河北省科学院能源研究所 2024-03-19 CN disclosed
CN-111057102-B Organophosphorus compounds, preparation method and application thereof 中国石油化工股份有限公司 2024-03-12 CN disclosed
CN-117089061-A Flame-retardant polyester polyol and preparation method and application thereof 万华化学集团股份有限公司 2023-11-21 CN disclosed
CN-113512452-B Diesel engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2023-10-10 CN disclosed
CN-114082309-B Polyphosphazene amide nanofiltration membrane with high-valence charge group on surface and preparation method thereof 北京碧水源膜科技有限公司 2023-10-10 CN disclosed
CN-113512451-B Lubricating oil composition for internal combustion engine and preparation method thereof 中国石油化工股份有限公司 2023-10-10 CN disclosed
CN-111057101-B Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2023-10-10 CN disclosed
CN-116867795-A Novel method for producing antibody-immunostimulant conjugate 第一三共株式会社 2023-10-10 CN disclosed
CN-113956284-B Porphyrin structure derivative and preparation method thereof, and dyeing-flame-retardant-anti-dripping integrated polyester 任元林 2023-10-03 CN disclosed
CN-116812915-A Nitrogen-nickel-copper doped carbon material and preparation method and application thereof 河北省科学院能源研究所 2023-09-29 CN disclosed
CN-111057108-B Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2023-08-15 CN disclosed
CN-111511750-B Macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2023-06-13 CN disclosed
CN-112143033-B Surface modified silicon dioxide and preparation method and application thereof 洛阳尖端技术研究院 2023-04-28 CN disclosed
US-20230086177-A1 PROCESS FOR PREPARING POLYETHER CARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2023-03-23 US disclosed
CN-114874456-B Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2023-03-03 CN disclosed
CN-114874456-B Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2023-03-03 CN disclosed
US-20230069332-A1 PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2023-03-02 US disclosed
US-20220411578-A1 PROCESS FOR PRODUCING POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-12-29 US disclosed
CN-115190893-A Method for producing polyether carbonate polyols 科思创德国股份有限公司 2022-10-14 CN disclosed
CN-114874456-A Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2022-08-09 CN disclosed
CN-114874456-A Method for modifying natural lignin of halogen-free flame-retardant degradable plastic 浙江农林大学 2022-08-09 CN disclosed
CN-114729115-A Method for producing polyether carbonate polyols 科思创知识产权两合公司 2022-07-08 CN disclosed
US-20220112172-A1 PROCESS FOR PRODUCING DIOL COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-04-14 US disclosed
CN-114082309-A Poly-phosphorus based amide nanofiltration membrane with high-valence charge groups on surface and preparation method thereof 北京碧水源膜科技有限公司 2022-02-25 CN disclosed
CN-112086638-B Method for reducing alkalinity of positive electrode material by using phosphorus-containing organic matter 中国科学院化学研究所 2021-12-21 CN disclosed
CN-113549484-A Acid-washing-free drawing coating powder for steel wire and preparation method thereof 南京华舜润滑制品有限公司 2021-10-26 CN disclosed
CN-113512452-A Lubricating oil composition for diesel engine and preparation method thereof 中国石油化工股份有限公司 2021-10-19 CN disclosed
CN-113512451-A Lubricating oil composition for internal combustion engine and preparation method thereof 中国石油化工股份有限公司 2021-10-19 CN disclosed
US-20210277181-A1 PROCESS FOR SEPARATING GASEOUS CONSTITUENTS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-09-09 US disclosed
CN-113004963-A Antirust high-lubricity cutting fluid and preparation process thereof 安徽联亚新材料有限公司 2021-06-22 CN disclosed
CN-112961724-A Extreme pressure antiwear agent and preparation method thereof 上海中器实业有限公司 2021-06-15 CN disclosed
CN-112961724-A Extreme pressure antiwear agent and preparation method thereof 上海中器实业有限公司 2021-06-15 CN disclosed
US-20210171426-A1 PROCESS FOR PRODUCING POLYOL COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-10 US disclosed
CN-110416621-B Method for treating inorganic solid electrolyte by using phosphorus-containing organic matter 中国科学院化学研究所 2021-05-18 CN disclosed
US-20210054145-A1 PROCESS FOR PREPARING POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-02-25 US disclosed
CN-112142776-A Process for preparing amino-tri (dimethylamino) phosphorochloridite 江苏奥克化学有限公司 2020-12-29 CN disclosed
CN-112143033-A Surface modified silicon dioxide and preparation method and application thereof 洛阳尖端技术研究院 2020-12-29 CN disclosed
CN-112086638-A Method for reducing alkalinity of positive electrode material by using phosphorus-containing organic matter 中国科学院化学研究所 2020-12-15 CN disclosed
CN-112029073-A Epoxy resin curing agent, reaction method, and curable epoxy resin composition 株式会社艾迪科 2020-12-04 CN disclosed
CN-111757902-A Method for producing polyether carbonate polyols 科思创知识产权两合公司 2020-10-09 CN disclosed
EP-3700911-A1 NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier SAS (FR) 2020-09-02 EP disclosed
CN-111607038-A Resin composition and product 洛阳尖端技术研究院 2020-09-01 CN disclosed
CN-111511750-A Novel macrocyclic derivatives, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2020-08-07 CN disclosed
US-10662314-B2 Method for producing polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2020-05-26 US disclosed
CN-111057110-A Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
CN-111057101-A Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
CN-111057102-A Organic phosphorus compound and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
CN-111057108-A Phosphoramidate compound and preparation method and application thereof 中国石油化工股份有限公司 2020-04-24 CN disclosed
US-10125217-B2 Method for producing polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2018-11-13 US disclosed
US-10040901-B2 Method for producing polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2018-08-07 US disclosed
US-20180079890-A1 METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS COVESTRO DEUTSCHLAND AG 2018-03-22 US disclosed
US-9815965-B2 Method for producing polyether carbonate polyols COVESTRO DEUTSCHLAND AG (DE) 2017-11-14 US disclosed
US-20170137569-A1 Method for Producing Polyether Carbonate Polyols COVESTRO DEUTSCHLAND AG (DE) 2017-05-18 US disclosed
US-20160264727-A1 METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2016-09-15 US disclosed
US-20160208080-A1 METHOD FOR PRODUCING POLYETHER CARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2016-07-21 US disclosed
EP-2204372-B1 Process for the preparation of thiophosphoric acid triamides with non-polar amines BASF SE (DE) 2012-01-04 EP disclosed
EP-1948670-B1 METHOD OF SEPARATING ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF APOLAR TERTIARY AMINES BASF SE (DE) 2010-11-24 EP disclosed
EP-2204372-A1 Process for the preparation of thiophosphoric acid triamides with non-polar amines BASF SE (DE) 2010-07-07 EP disclosed
EP-2146982-A2 AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS Vertex Pharmaceuticals Incorporated (US) 2010-01-27 EP disclosed
WO-2008128009-A2 AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2008-10-23 WO disclosed
EP-1954277-A2 AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS Vertex Pharmceuticals Incorporated (US) 2008-08-13 EP disclosed
WO-2007056221-A2 AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-05-18 WO disclosed
EP-1296961-B1 1,4-DIAZEPAN-2,5-DIONE DERIVATIVES AND THEIR USE AS NK-1 RECEPTOR ANTAGONISTS HOFFMANN LA ROCHE (CH) 2007-02-14 EP disclosed
WO-2005075486-A1 METHOD OF SYNTHESIZING COMPOUNDS HAVING A PHOSPHORUS-FLUORINE-18 BOND THE UNIVERSITY OF ALBERTA, SIMON FRASER UNIVERSITY, THE UNIVERSITY OF VICTORIA, THE UNIVERSITY OF BRITISH COLUMBIA AND CARLETON UNIVERSITY, COLLECTIVELY DOING BUSINESS ASTRIUMF (CA) 2005-08-18 WO disclosed
US-20050175534-A1 Method of synthesizing compounds having a phosphorus-fluorine-18 bond THE UNIVERSITY OF ALBERTA, SIMON FRASER UNIVERSITY, THE UNIVERSITY OF VICTORIA, THE UNIVERSITY OF BRITISH COLUMBIA AND CARLETON UNIVERSITY, COLLECTIVELY D/B/A TRIUMF (CA) 2005-08-11 US disclosed
EP-1296961-A1 1,4-DIAZEPAN-2,5-DIONE DERIVATIVES AND THEIR USE AS NK-1 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2003-04-02 EP disclosed
US-6452001-B2 1,4-DIAZEPINE-2-ONE DERIVATIVES AS NEUROKININ ANTAGONIST HOFFMANN-LA ROCHE INC. 2002-09-17 US disclosed
US-20020010174-A1 Diazapane derivatives useful as antagonists of neurokinin 1 receptor and methods for their formation F. HOFFMANN-LA ROCHE AG (CH) 2002-01-24 US disclosed
WO-2001090083-A1 1,4-DIAZEPAN-2,5-DIONE DERIVATIVES AND THEIR USE AS NK-1 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2001-11-29 WO disclosed
US-5446134-A Reacting bis(fluorosulfonyl)methane salt with cyanogen halide or pseudohalide CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1995-08-29 US disclosed
EP-0339237-B1 PHENOL SUBSTITUTED GEM-DIPHOSPHONATE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYMPHAR S.A. (CH) 1992-12-30 EP disclosed
US-5043330-A Antiinflammatory and hypotensive agents; antihyperlipemia SYMPHAR S.A. (CH) 1991-08-27 US disclosed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
EP-0339237-A2 Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them SYMPHAR S.A. (CH) 1989-11-02 EP disclosed
US-4235913-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1980-11-25 US disclosed
US-4165323-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1979-08-21 US disclosed
US-4118559-A CNS AGENTS, ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1978-10-03 US disclosed
US-4034064-A Hydrogen peroxide stabilization with triamides of phosphorus PPG INDUSTRIES, INC. (US) 1977-07-05 US disclosed
US-3969440-A FIREPROOFING SCOTT PAPER COMPANY (US) 1976-07-13 US disclosed
US-3969440-A FIREPROOFING SCOTT PAPER COMPANY (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112172-A1 PROCESS FOR PRODUCING DIOL CA4, CA2, CA1 TP53 4654/4885TDP1 3023/4885
US-20050175534-A1 Method of synthesizing compounds having a phosphorus-fluorine-18 bond PHOSPHO1, PNP, PFAS TP53 1660/4885TDP1 2409/4885
US-12595433-B2 Organic phosphorus compound, preparation method therefor, and uses thereof NOTUM, GC, PHOSPHO1 TP53 4076/4885TDP1 320/4885
US-20210171426-A1 PROCESS FOR PRODUCING POLYOL HAO2, HACL2, PHOSPHO1 TP53 4629/4885TDP1 1991/4885
US-20250034476-A1 ORGANIC PHOSPHORUS COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF SOST, NOTUM, WEE1 TP53 2878/4885TDP1 229/4885
US-20020010174-A1 Diazapane derivatives useful as antagonists of neurokinin 1 receptor and methods for their formation BDKRB2, NPSR1, BDKRB1 TP53 4674/4885TDP1 2329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.