Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12138371 | 0.87 | DNM1 (0.32) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL18330665 | 0.87 | DNM1 (0.32) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL21337184 | 0.86 | DNM1 (0.35) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7680246 | 0.85 | DNM1 (0.31) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL26720171 | 0.83 | DNM1 (0.36) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL18710645 | 0.83 | GABRR1 (0.35) | — | |
| SCHEMBL25896186 | 0.83 | — | — | |
| SCHEMBL13128007 | 0.82 | DNM1 (0.32) | DNM1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7149510 | 0.81 | OPRM1 (0.30) | — | |
| SCHEMBL31333162 | 0.81 | DNM1 (0.35) | DNM1ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | VILNIUS UNIVERSITY (LT) | 2025-03-11 | — | — | US | disclosed |
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | VILNIUS UNIVERSITY (LT) | 2024-01-04 | — | — | US | disclosed |
| EP-4299062-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| WO-2021034853-A1 | ATTACHING NUCLEOTIDES TO A POLYNUCLEOTIDE WITH A POLYMERASE | ILLUMINA, INC. (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000736-A1 | INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES | APP, APBA1, IAPP | DNM1 1983/4885ALDH1A1 3244/4885MEN1 1754/4885 |
| US-12246000-B2 | Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides | APP, APBA1, IAPP | DNM1 1983/4885ALDH1A1 3244/4885MEN1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.