Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | CNR1 | P21554 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | BLM | P54132 | 2/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | FAAH | O00519 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287721 | 1.00 | MEN1 (0.77) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL18240162 | 0.95 | CNR1 (0.79) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL2639337 | 0.95 | CNR1 (0.79) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL4155101 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL16599896 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL18240167 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL23027722 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL2476433 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL18240169 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD | |
| SCHEMBL379158 | 0.95 | FAAH (0.78) | MEN1KMT2ACNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052631-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052631-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | SNRPE, FABP1, RNASE1 | MEN1 3943/4885KMT2A 2793/4885CNR1 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.