Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028603 | 0.87 | ALDH1A1 (0.42) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028607 | 0.80 | TP53 (0.38) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028602 | 0.80 | TP53 (0.38) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028734 | 0.79 | ALDH1A1 (0.48) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL18362136 | 0.77 | ALDH1A1 (0.50) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028737 | 0.74 | ALDH1A1 (0.46) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028674 | 0.73 | ITGB3 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2ITGB3 | |
| SCHEMBL18072327 | 0.72 | ALDH1A1 (0.52) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL18072243 | 0.72 | ALDH1A1 (0.52) | TP53RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL23028606 | 0.71 | ALDH1A1 (0.40) | TP53RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034548-A1 | MITOCHONDRIAL MODULATION TO IMPROVE METABOLIC SYNDROME DURING AGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |