Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028621 | 0.87 | MAOA (0.46) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL29508438 | 0.87 | MAOA (0.46) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL23013668 | 0.84 | MAOA (0.43) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL23028553 | 0.83 | MAOA (0.42) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL9717426 | 0.79 | SLC6A2 (0.46) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL27893428 | 0.78 | BRD4 (0.44) | BRD4PAX8NPSR1CREBBPRAB9A | |
| SCHEMBL30695840 | 0.77 | MAOA (0.45) | MAOAUSP2GAAALOX15RAD51 | |
| SCHEMBL31453143 | 0.77 | PAX8 (0.51) | BRD4PAX8GAANPSR1CREBBP | |
| SCHEMBL8018111 | 0.77 | PAX8 (0.55) | BRD4PAX8GAANPSR1CREBBP | |
| SCHEMBL19463917 | 0.76 | MAOA (0.46) | MAOANLRP3TAS1R3TAS1R1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032934-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |