Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028694 | 0.85 | TSHR (0.40) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028668 | 0.84 | TSHR (0.42) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028667 | 0.84 | TSHR (0.42) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL4104605 | 0.80 | TSHR (0.37) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028699 | 0.79 | TSHR (0.42) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028698 | 0.78 | TSHR (0.45) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| Guanidinoethyldisulfide SCHEMBL145590 | 0.71 | TSHR (0.69) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL23028691 | 0.70 | ALOX15 (0.37) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL8961402 | 0.69 | ALOX15 (0.42) | TSHRHIF1AALOX15CYP1A2SMN1; SMN2 | |
| SCHEMBL28773277 | 0.69 | ALOX15 (0.39) | TSHRALOX15CYP1A2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021034548-A1 | MITOCHONDRIAL MODULATION TO IMPROVE METABOLIC SYNDROME DURING AGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |