SCHEMBL23028798

SCHEMBL23028798

c1ccc(-c2cc(-c3cc4c5c(c3)Oc3ccccc3C5(c3ccccc3)c3ccccc3O4)cc(-c3cccnc3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.56
BACE1 P56817 6/20 0.38
DHODH Q02127 1/20 0.38
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 3/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 1/20 0.36
NPC1 O15118 1/20 0.36
PDK2 Q15119 3/20 0.36
CYP2A6 P11509 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
KMO O15229 1/20 0.35
PGR P06401 1/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25453502 0.81 CYP19A1 (0.40) CYP19A1BACE1KDM4ERAB9AALDH1A1
SCHEMBL21732760 0.80 CYP19A1 (0.37) CYP19A1BACE1KDM4EGAAALDH1A1
SCHEMBL21732757 0.80 KMT2A (0.37) CYP19A1KDM4EALDH1A1SMN1; SMN2
SCHEMBL25453369 0.80 KMT2A (0.37) CYP19A1KDM4EGLARAB9AALDH1A1
SCHEMBL21732759 0.80 KMT2A (0.35) CYP19A1BACE1KDM4EGLARAB9A
SCHEMBL21732767 0.80 KMT2A (0.35) CYP19A1BACE1KDM4EGLARAB9A
SCHEMBL23028844 0.79 LMNA (0.33) BACE1KDM4EGAAALDH1A1LMNA
SCHEMBL21732776 0.79 KMT2A (0.40) CYP19A1BACE1KDM4EALDH1A1
SCHEMBL21732764 0.79 CYP19A1 (0.38) CYP19A1BACE1KDM4EGAAALDH1A1
SCHEMBL21732541 0.78 KMT2A (0.38) CYP19A1BACE1KDM4EGLARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021034089-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-02-25 WO disclosed