SCHEMBL23028844

SCHEMBL23028844

c1ccc(-c2cc3c4c(c2)Oc2ccccc2C4(c2ccccc2)c2ccccc2O3)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
ALOX5 P09917 2/20 0.32
AHR P35869 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAOA P21397 1/20 0.31
HSD11B1 P28845 1/20 0.31
BACE1 P56817 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
CFTR P13569 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23028795 0.89 NOTUM (0.41) LMNAHSD17B10BACE1MAPT
SCHEMBL23028855 0.88 BACE1 (0.36) LMNAHTTALOX5ALDH1A1CYP2C9
SCHEMBL23028845 0.85 GPR84 (0.32) HTTHPGD
SCHEMBL23028801 0.85 L3MBTL1 (0.37) LMNAHTTALDH1A1CYP2C9HPGD
SCHEMBL15713395 0.85 LMNA (0.37) LMNAHTTALOX5ALDH1A1HSD17B10
SCHEMBL23028707 0.85 ALDH1A1 (0.35) LMNAHTTALOX5AHRALDH1A1
SCHEMBL23028838 0.85 LMNA (0.39) LMNAHTTALOX5AHRMAOA
SCHEMBL2606059 0.84 ALDH1A1 (0.33) HTTALOX5AHRALDH1A1CYP2C9
SCHEMBL4388225 0.82 ALOX5 (0.41) LMNAALOX5AHRMAOAKDM4E
SCHEMBL23028785 0.82 AHR (0.40) LMNAALOX5AHRMAPTCFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021034089-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-02-25 WO disclosed