Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330871 | 0.82 | MAPT (0.32) | HRH4HTR3AMAPT | |
| SCHEMBL21287187 | 0.81 | TOP2A (0.36) | TOP2AHRH4HTR3AMAPT | |
| SCHEMBL23331262 | 0.80 | TP53 (0.40) | NPC1POLBMAPT | |
| SCHEMBL23331056 | 0.80 | PIK3CA (0.38) | — | |
| SCHEMBL24857618 | 0.77 | KDM4E (0.35) | HRH4HTR3AHRH3NPC1POLB | |
| SCHEMBL24978035 | 0.76 | LMNA (0.46) | KAT2BBRD9NPC1POLBMAPT | |
| SCHEMBL23331263 | 0.76 | MAPT (0.36) | NPC1MAPT | |
| SCHEMBL23330661 | 0.76 | KMT2A (0.41) | NPC1POLBMAPT | |
| SCHEMBL23330539 | 0.73 | HRH4 (0.33) | HRH4HTR3AHRH3 | |
| SCHEMBL23330521 | 0.73 | HTT (0.33) | HRH4HTR3AHRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032004-A9 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-03-25 | — | — | WO | disclosed |
| WO-2021032004-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-02-25 | — | — | WO | disclosed |