Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23029863 | 0.82 | TOP2A (0.36) | MAPTHRH4HTR3A | |
| SCHEMBL23331056 | 0.76 | PIK3CA (0.38) | — | |
| SCHEMBL23331262 | 0.76 | TP53 (0.40) | MAPTKDM4EKMT2A | |
| SCHEMBL23330631 | 0.76 | MAPT (0.37) | MAPTKDM4EKMT2AHRH4 | |
| SCHEMBL23330678 | 0.76 | TSHR (0.42) | KDM4EKMT2A | |
| SCHEMBL24857618 | 0.73 | KDM4E (0.35) | MAPTKDM4EKMT2AHRH4HTR3A | |
| SCHEMBL24978035 | 0.73 | LMNA (0.46) | MAPTKDM4EKMT2A | |
| SCHEMBL23331263 | 0.73 | MAPT (0.36) | MAPTKDM4EKMT2A | |
| SCHEMBL23330539 | 0.69 | HRH4 (0.33) | HRH4HTR3A | |
| SCHEMBL23330521 | 0.69 | HTT (0.33) | MAPTHRH4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083380-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海科技大学 | 2021-05-06 | — | — | WO | disclosed |