Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23029946 | 0.81 | HAVCR2 (0.39) | HAVCR2HPGDLMNATSHRPDE10A | |
| SCHEMBL23029977 | 0.75 | HAVCR2 (0.35) | HAVCR2HPGDLMNATSHRPDE10A | |
| SCHEMBL16565475 | 0.65 | AHR (0.54) | HAVCR2HPGDPDE10AHSD17B10MAPT | |
| SCHEMBL19761029 | 0.65 | LMNA (0.38) | HAVCR2HPGDLMNATSHRPDE10A | |
| SCHEMBL1044937 | 0.65 | CHEK1 (0.34) | — | |
| SCHEMBL405895 | 0.63 | PDE10A (0.57) | HAVCR2PDE10APDE5APDE4D | |
| SCHEMBL31167556 | 0.63 | PDE10A (0.57) | HAVCR2LMNAPDE10AHSD17B10MAPT | |
| SCHEMBL25342261 | 0.62 | KDM4E (0.35) | HAVCR2HPGDLMNAPDE10AL3MBTL1 | |
| SCHEMBL19761037 | 0.62 | TLR9 (0.34) | L3MBTL1MAPT | |
| SCHEMBL31329841 | 0.62 | HAVCR2 (0.36) | HAVCR2HPGDLMNATSHRPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019521-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | Blueray Therapeutics (Shanghai) Co., Ltd (CN) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021032004-A9 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-03-25 | — | — | WO | disclosed |
| WO-2021032004-A1 | AZAHETEROARYL COMPOUND AND APPLICATION THEREOF | 上海青煜医药科技有限公司 | 2021-02-25 | — | — | WO | disclosed |