Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117149 | 0.90 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28016171 | 0.83 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2303007 | 0.82 | ATM (0.42) | TSHRALDH1A1CYP3A4HPGDATM | |
| SCHEMBL29403092 | 0.81 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2304685 | 0.80 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2303003 | 0.79 | TSHR (0.49) | TSHRALDH1A1THRB | |
| SCHEMBL8089941 | 0.78 | TSHR (0.65) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL308812 | 0.77 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL42398 | 0.77 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL26187833 | 0.77 | TSHR (0.63) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372516-B2 | (Meth)acrylate phosphonic esters as adhesion promoters | BASF SE (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2350215-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100112362-A1 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | CIBA CORPORATION (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010049322-A2 | (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS | BASF SE (DE) | 2010-05-06 | — | — | WO | disclosed |