SCHEMBL2303003

SCHEMBL2303003

C=C(C)C(=O)OCCCP(=O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975816 0.81 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1367290 0.81 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL29403126 0.80 ALDH1A1 (0.44) TSHRTHRBALDH1A1
SCHEMBL2304752 0.79 TSHR (0.54) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2303000 0.79 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL14007299 0.78 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL41489 0.78 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL11843082 0.78 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28789024 0.77 TSHR (0.56) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1366752 0.76 TSHR (0.59) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372516-B2 (Meth)acrylate phosphonic esters as adhesion promoters BASF SE (DE) 2013-02-12 US disclosed
EP-2350215-A2 (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS BASF SE (DE) 2011-08-03 EP disclosed
US-20100112362-A1 (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS CIBA CORPORATION (US) 2010-05-06 US disclosed
WO-2010049322-A2 (METH)ACRYLATE PHOSPHONIC ESTERS AS ADHESION PROMOTERS BASF SE (DE) 2010-05-06 WO disclosed