Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23030527 | 0.87 | CHKA (0.46) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL13034802 | 0.84 | CHKA (0.53) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL7334680 | 0.83 | CHKA (0.52) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL7329592 | 0.82 | CHKA (0.47) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL5803729 | 0.77 | CHKA (0.53) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL4435638 | 0.77 | ITGB3 (0.46) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL7364014 | 0.76 | CHKA (0.44) | CHKADPP4DPP8DPP9DPP7 | |
| Ammonia Solution, Strong SCHEMBL5844271 | 0.76 | CHKA (0.52) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL22857558 | 0.75 | CHKA (0.50) | CHKADPP4DPP8DPP9DPP7 | |
| SCHEMBL21101188 | 0.75 | CHKA (0.50) | CHKADPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032933-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |