Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384585 | 0.81 | L3MBTL1 (0.49) | — | |
| SCHEMBL7329592 | 0.79 | CHKA (0.47) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL8633125 | 0.79 | F10 (0.52) | HRH3TSHRDPP4DPP8DPP9 | |
| SCHEMBL1976988 | 0.78 | AKR1C3 (0.46) | — | |
| SCHEMBL23030554 | 0.77 | CHKA (0.48) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL7334680 | 0.77 | CHKA (0.52) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL8698089 | 0.76 | ITGB3 (0.43) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL8631652 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2BHRH3DPP4DPP8 | |
| SCHEMBL8635011 | 0.75 | ITGB3 (0.48) | ITGB3ITGA2BHRH3CYP2C9TSHR | |
| SCHEMBL17730142 | 0.75 | CPB2 (0.42) | HRH3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531537-B2 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20050282808-A1 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282808-A1 | Benzofuran derivative | F12, F2, F11 | ITGB3 1145/4885ITGA2B 839/4885HRH3 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.