SCHEMBL2303084

SCHEMBL2303084

COc1[c]c(OC)c2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPK1 P28482 1/20 0.41
NQO1 P15559 1/20 0.39
HPGD P15428 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ERN1 O75460 1/20 0.39
POLB P06746 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2885777 0.82 ALDH1A1 (0.43) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL20564340 0.81 ALDH1A1 (0.41) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL29094151 0.79 NQO1 (0.38) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL5599012 0.79 ALDH1A1 (0.41) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL15353127 0.79 ALDH1A1 (0.40) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL2304155 0.74 BTK (0.37) ALDH1A1KDM4EMAPK1CYP1A2CYP2A6
SCHEMBL18886576 0.73 MAPT (0.37) ALDH1A1KDM4ESMN1; SMN2MAPK1HPGD
SCHEMBL12505381 0.73 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDNPSR1ERN1
SCHEMBL16909846 0.70 NQO1 (0.46) ALDH1A1KDM4ESMN1; SMN2MAPK1NQO1
SCHEMBL2302460 0.70 KDM4E (0.43) ALDH1A1KDM4EMAPK1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251049-B1 PHOTOPOLYMERISABLE REGISTRATION MATERIALS, PHOTORESIST LAYERS AND LITHOGRAPHIC PRINTING PLATES BASED ON THESE REGISTRATION MATERIALS BASF Aktiengesellschaft (DE) 1992-09-09 EP claimed
US-4719297-A Acylphosphine compounds and their use as photoinitiators BASF AKTIENGESELLSCHAFT (DE) 1988-01-12 US claimed
EP-0062839-B1 ACYLPHOSPHINE COMPOUNDS AND THEIR USE BASF Aktiengesellschaft (DE) 1984-11-21 EP claimed
EP-0047902-B1 ACYLPHOSPHINESULFIDE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1984-11-07 EP claimed
EP-0057474-B1 ACYLPHOSPHINE OXDE COMPOUNDS, THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1984-10-17 EP claimed
US-4298738-A PHOTOINITIATORS IN PHOTOPOLYMERIZABLE COATINGS AND IMKS BASF AKTIENGESELLSCHAFT (DE) 1981-11-03 US claimed
WO-2023190912-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 日本ポリケム株式会社 2023-10-05 WO disclosed
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
CN-113874402-B Polar group-containing olefin copolymer 国立大学法人东京大学 2023-04-04 CN disclosed
WO-2023033030-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 国立大学法人 東京大学 2023-03-09 WO disclosed
EP-3208285-B2 PRODUCTION METHOD OF AN ETHYLENE AND/OR ALPHA-OLEFIN-BASED IONOMER JAPAN POLYETHYLENE CORP (JP) 2023-01-25 EP disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
CN-113874402-A Polar group-containing olefin copolymer 国立大学法人东京大学 2021-12-31 CN disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed
EP-0446175-A2 Mixture of photoinitiators CIBA-GEIGY AG (CH) 1991-09-11 EP disclosed
EP-0369810-A2 PAF antagonists as anti-hyperendothelinemia agents Takeda Chemical Industries, Ltd. (JP) 1990-05-23 EP disclosed
US-4719297-A Acylphosphine compounds and their use as photoinitiators BASF AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed
US-4710523-A DISCOLORATION, WEAR RESISTANT SURFACE COATING, FINISHES, AND PRINTING INK BASF AKTIENGESELLSCHAFT (DE) 1987-12-01 US disclosed
US-4522693-A Photopolymerizable composition with acylphosphine sulfide photoinitiator and method BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US disclosed
US-4298738-A PHOTOINITIATORS IN PHOTOPOLYMERIZABLE COATINGS AND IMKS BASF AKTIENGESELLSCHAFT (DE) 1981-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885KDM4E 2651/4885SMN1; SMN2 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.