SCHEMBL2304155

SCHEMBL2304155

CCOc1[c]c(OCC)c2ccccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.37
ALOX5 P09917 1/20 0.36
TLR8 Q9NR97 1/20 0.36
MPO P05164 1/20 0.35
NR1I2 O75469 1/20 0.35
ELANE P08246 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
HTR2A P28223 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20564112 0.82 CYP1A2 (0.37) BTKALOX5TLR8NR1I2ELANE
SCHEMBL8125964 0.81 L3MBTL1 (0.36) BTKALOX5TLR8NR1I2ELANE
SCHEMBL20562074 0.81 BTK (0.36) BTKALOX5TLR8NR1I2ELANE
SCHEMBL644629 0.75 GPR84 (0.44) BTKALOX5TLR8NR1I2ELANE
SCHEMBL29694174 0.75 GPR84 (0.44) BTKALOX5TLR8NR1I2ELANE
SCHEMBL2303084 0.74 ALDH1A1 (0.41) ALOX5ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL1452144 0.73 ALOX5 (0.37) ALOX5MPOELANELMNAALDH1A1
SCHEMBL2253339 0.72 LTA4H (0.39) TLR8L3MBTL1LMNAALDH1A1KMT2A
SCHEMBL18886576 0.70 MAPT (0.37) BTKTLR8L3MBTL1ALDH1A1KMT2A
SCHEMBL20694984 0.70 NQO1 (0.33) ALOX5TLR8MPOL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023190912-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 日本ポリケム株式会社 2023-10-05 WO disclosed
EP-3978537-B1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER UNIV TOKYO (JP) 2023-09-13 EP disclosed
CN-113874402-B Polar group-containing olefin copolymer 国立大学法人东京大学 2023-04-04 CN disclosed
WO-2023033030-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER AND METHOD FOR PRODUCING SAME 国立大学法人 東京大学 2023-03-09 WO disclosed
EP-3208285-B2 PRODUCTION METHOD OF AN ETHYLENE AND/OR ALPHA-OLEFIN-BASED IONOMER JAPAN POLYETHYLENE CORP (JP) 2023-01-25 EP disclosed
US-20220220239-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER THE UNIVERSITY OF TOKYO (JP) 2022-07-14 US disclosed
CN-113874402-A Polar group-containing olefin copolymer 国立大学法人东京大学 2021-12-31 CN disclosed
CN-106573998-B Olefin polymerization catalyst and process for producing olefin polymer 日本聚乙烯株式会社 2021-10-12 CN disclosed
WO-2020241715-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER 国立大学法人東京大学 2020-12-03 WO disclosed
US-10717855-B2 Production method of ethylene-based ionomer and ethylene-based ionomer JAPAN POLYETHYLENE CORPORATION (JP) 2020-07-21 US disclosed
CN-105940016-A Method for producing ethylene/unsaturated carboxylic acid copolymer, and said copolymer 日本聚乙烯株式会社 2016-09-14 CN disclosed
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER JAPAN POLYPROPYLENE CORPORATION (JP) 2016-08-18 US disclosed
EP-3050892-A1 IMINE COMPOUND AND NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Japan Polypropylene Corporation (JP) 2016-08-03 EP disclosed
CN-105593235-A Imine compound, novel catalyst for olefin polymerization, and method for producing olefin polymer JAPAN POLYPROPYLENE CORP 2016-05-18 CN disclosed
EP-2351761-B1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX JAPAN POLYPROPYLENE CORP (JP) 2015-12-02 EP disclosed
CN-102197040-B Metal complex, method for producing alpha-olefin polymer using same, and method for producing alpha-olefin/ acrylate copolymer JAPAN POLYPROPYLENE CORP 2014-12-31 CN disclosed
US-8618319-B2 Metal complex and method for producing α-olefin polymer and method for producing α-olefin/(meth)acrylate copolymer using the same JAPAN POLYPROPYLENE CORPORATION (JP) 2013-12-31 US disclosed
CN-102197040-A Novel metal complex, method for producing alpha-olefin polymer using same, and method for producing alpha-olefin/ acrylate copolymer JAPAN POLYPROPYLENE CORP 2011-09-21 CN disclosed
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2011-09-01 US disclosed
EP-2351761-A1 NOVEL METAL COMPLEX, AND METHOD FOR PRODUCING -OLEFIN POLYMER AND METHOD FOR PRODUCING -OLEFIN/(METH)ACRYLATE COPOLYMER EACH USING THE METAL COMPLEX Japan Polypropylene Corporation (JP) 2011-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237184-A1 IMINE COMPOUND, NOVEL CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER ODC1, MACF1, MOGAT2 BTK 1821/4885ALOX5 404/4885TLR8 2702/4885
US-20110213110-A1 NOVEL METAL COMPLEX AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER AND METHOD FOR PRODUCING ALPHA-OLEFIN/(METH)ACRYLATE COPOLYMER USING THE SAME OPRD1, OSTC, COG7 BTK 3753/4885ALOX5 224/4885TLR8 3467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.