Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | WNT1 | P04628 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CCNC | P24863 | 2/20 | 0.42 |
| ▸ | CDK8 | P49336 | 2/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714669 | 0.88 | PIM1 (0.40) | PIM1PIM2HPSE | |
| SCHEMBL29479615 | 0.87 | MAOA (0.43) | PIM1PIM2HPSE | |
| SCHEMBL28706416 | 0.87 | MAOA (0.43) | PIM1PIM2HPSE | |
| SCHEMBL29479701 | 0.87 | KDM4E (0.44) | PIM1PIM2DYRK1AWNT1GSK3B | |
| SCHEMBL28714630 | 0.87 | KDM4E (0.44) | PIM1PIM2DYRK1AWNT1GSK3B | |
| SCHEMBL28714674 | 0.86 | PIM1 (0.44) | PIM1PIM2METDYRK1AWNT1 | |
| SCHEMBL29479641 | 0.86 | PIM1 (0.44) | PIM1PIM2METDYRK1AWNT1 | |
| SCHEMBL28713867 | 0.86 | GRK5 (0.51) | PIM1PIM2MET | |
| SCHEMBL29479792 | 0.86 | GRK5 (0.51) | PIM1PIM2MET | |
| SCHEMBL29479735 | 0.85 | S1PR1 (0.41) | PIM1PIM2METHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |