Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479679 | 1.00 | HPSE (0.42) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29479720 | 0.91 | GPR119 (0.42) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28714608 | 0.91 | GPR119 (0.42) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL23012350 | 0.89 | MAPT (0.47) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL28710708 | 0.83 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL23033416 | 0.83 | JMJD6 (0.43) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL23033644 | 0.81 | HDAC6 (0.40) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29479777 | 0.81 | SMN1; SMN2 (0.59) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28711116 | 0.81 | SMN1; SMN2 (0.59) | HPSESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL23033305 | 0.81 | HDAC6 (0.40) | SMN1; SMN2NPC1RAB9AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |