Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.62 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.41 |
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751150 | 0.86 | SCD (0.47) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL4949255 | 0.83 | ALDH1A1 (0.46) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL29915607 | 0.82 | GRM1 (0.55) | SCDSCD5CCNT1CDK9CNR1 | |
| SCHEMBL17222999 | 0.82 | GRM1 (0.55) | SCDSCD5CCNT1CDK9CNR1 | |
| SCHEMBL28438757 | 0.82 | TRPV1 (0.44) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL16422890 | 0.81 | MAPT (0.44) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL23064245 | 0.80 | ALDH1A1 (0.48) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL28437327 | 0.79 | MAPT (0.43) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL4776359 | 0.78 | MAPT (0.50) | SCDSCD5MAPTLMNAHTT | |
| SCHEMBL4602817 | 0.78 | ALDH1A1 (0.66) | MAPTLMNAHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784234-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |