Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751150 | 0.89 | SCD (0.47) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL23291429 | 0.86 | MAPT (0.49) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL16422890 | 0.86 | MAPT (0.44) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL8013522 | 0.86 | MAPT (0.39) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL28437327 | 0.84 | MAPT (0.43) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL23034993 | 0.83 | SCD (0.62) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL22324799 | 0.83 | CPS1 (0.48) | ALDH1A1PDE4BPDE4DCCNT1CDK9 | |
| SCHEMBL5376595 | 0.82 | ALDH1A1 (0.48) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL15524420 | 0.82 | ADAM10 (0.43) | ALDH1A1ALOX15MAPTNPC1RAB9A | |
| SCHEMBL15524421 | 0.82 | ADAM10 (0.43) | ALDH1A1ALOX15MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318999-A1 | Tricyclic Benzimidazoles and Their Use as Metabotropic Glutamate Receptor Modulators | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318999-A1 | Tricyclic Benzimidazoles and Their Use as Metabotropic Glutamate Receptor Modulators | GRM2, GRM1, GRIN2B | ALDH1A1 1887/4885ALOX15 3925/4885MAPT 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.