Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.47 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20727281 | 0.97 | HTR6 (0.49) | HTR6SFRP1PKMNR1H3WNT3 | |
| Hydrochloric Acid SCHEMBL21955534 | 0.96 | HTR6 (0.48) | HTR6SFRP1PKMNR1H3WNT3 | |
| Hypochlorous Acid SCHEMBL23035161 | 0.92 | HTR6 (0.48) | HTR6PKM | |
| SCHEMBL20727270 | 0.89 | HTR6 (0.47) | HTR6SFRP1PKMWNT3 | |
| SCHEMBL20727275 | 0.89 | HTR6 (0.51) | HTR6PKM | |
| Hydrochloric Acid SCHEMBL21955532 | 0.89 | HTR6 (0.46) | HTR6SFRP1PKMWNT3 | |
| Hydrochloric Acid SCHEMBL21955559 | 0.88 | HTR6 (0.52) | HTR6PKM | |
| SCHEMBL20727287 | 0.88 | HTR6 (0.39) | HTR6PKM | |
| Hydrochloric Acid SCHEMBL21955571 | 0.87 | HTR6 (0.39) | HTR6PKM | |
| SCHEMBL20723645 | 0.85 | PKM (0.42) | HTR6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649124-B1 | FLUOROPIPERIDINE COMPOUNDS AS PURE 5-HT6 RECEPTOR ANTAGONISTS | SUVEN LIFE SCIENCES LTD (IN) | 2021-03-03 | — | — | EP | claimed |