Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036328 | 1.00 | PPARG (0.49) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL23036396 | 0.92 | PPARG (0.47) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL23036394 | 0.92 | PPARG (0.47) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL24740963 | 0.92 | LMNA (0.51) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL24062073 | 0.92 | ALDH1A1 (0.44) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL23036558 | 0.91 | ALDH1A1 (0.46) | PPARGHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL23036562 | 0.91 | ALDH1A1 (0.46) | PPARGHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL23036303 | 0.91 | PPARG (0.45) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL23036301 | 0.91 | PPARG (0.45) | PPARGRXRAHPGDKDM4EALDH1A1 | |
| SCHEMBL23036226 | 0.90 | PPARG (0.48) | PPARGRXRAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784228-A1 | ANTICANCER INDENES, INDANES, AZAINDENES, AZAINDANES, PHARMACEUTICAL COMPOSITIONS AND USES | ADT Pharmaceuticals, LLC (US) | 2021-03-03 | — | — | EP | claimed |
| CN-112020354-A | Anti-cancer indenes, indanes, aza-indenes, aza-indanes, pharmaceutical compositions and uses | ADT制药有限责任公司 | 2020-12-01 | — | — | CN | claimed |
| EP-3784228-A1 | ANTICANCER INDENES, INDANES, AZAINDENES, AZAINDANES, PHARMACEUTICAL COMPOSITIONS AND USES | ADT Pharmaceuticals, LLC (US) | 2021-03-03 | — | — | EP | disclosed |
| CN-112020354-A | Anti-cancer indenes, indanes, aza-indenes, aza-indanes, pharmaceutical compositions and uses | ADT制药有限责任公司 | 2020-12-01 | — | — | CN | disclosed |