Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.47 |
| ▸ | MGMT | P16455 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487338 | 0.84 | CDK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL23113063 | 0.78 | CDK1 (0.35) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4654620 | 0.77 | CDK1 (0.35) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11197621 | 0.75 | CDK1 (0.37) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11184649 | 0.73 | CDK1 (0.36) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11183310 | 0.73 | HTT (0.35) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11188636 | 0.73 | CDK1 (0.36) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11051576 | 0.72 | LMNA (0.56) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL23037276 | 0.72 | CDK1 (0.46) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL23111940 | 0.71 | CDK1 (0.32) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11603380-B2 | Antiviral acyclonucleoside analogues for use in treating a viral infection | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-03-14 | — | — | US | disclosed |
| US-20210079031-A1 | NEW ANTIVIRAL ACYCLONUCLEOSIDE ANALOGUES | NEOVIRTECH (FR) | 2021-03-18 | — | — | US | disclosed |
| EP-3784680-A1 | NEW ANTIVIRAL ACYCLONUCLEOSIDE ANALOGUES | Centre national de la recherche scientifique (FR) | 2021-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11603380-B2 | Antiviral acyclonucleoside analogues for use in treating a viral infection | TYMP, EIF2AK2, ENTPD5 | CDK1 621/4885CCNB1 825/4885CCNA2 229/4885 |
| US-20210079031-A1 | NEW ANTIVIRAL ACYCLONUCLEOSIDE ANALOGUES | TYMP, EIF2AK2, PNP | CDK1 256/4885CCNB1 485/4885CCNA2 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.