Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800782 | 0.82 | CASP1 (0.47) | LMNACASP1CYP1A2ALDH1A1 | |
| Alcohol SCHEMBL8078657 | 0.76 | LMNA (0.46) | LMNACASP1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL131290 | 0.74 | — | — | |
| Alcohol SCHEMBL11191431 | 0.74 | LMNA (0.46) | LMNACASP1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL31484351 | 0.72 | LMNA (1.00) | LMNACASP1CYP1A2KDM4EALDH1A1 | |
| Alcohol SCHEMBL9588110 | 0.72 | LMNA (0.44) | LMNACASP1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL23037265 | 0.72 | CDK1 (0.47) | LMNACASP1CDK1CCNB1MGMT | |
| SCHEMBL11769469 | 0.72 | LMNA (0.45) | LMNA | |
| Ethylene Glycol SCHEMBL8570947 | 0.72 | CASP1 (0.45) | LMNACASP1CYP1A2ALDH1A1NUDT1 | |
| SCHEMBL28235429 | 0.72 | CASP1 (0.45) | LMNACASP1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152784-A1 | Fluoroalkyl groups containing salts of beta-alkylaminopropionic-acid esters, process for their preparation and their use in the preparation of aqueous polyacrylate dispersions containing fluoroalkyl groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-28 | — | — | EP | disclosed |