Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289848 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL6551442 | 0.85 | ALDH1A1 (0.61) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL827585 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL9647951 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL31255865 | 0.81 | CTSD (0.59) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL7108165 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL195311 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL1133328 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL6968113 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2ANPC1RAB9A | |
| SCHEMBL8576742 | 0.81 | CTSD (0.59) | ALDH1A1CTSDKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786143-A1 | PROCESS FOR PREPARING FLUOROBENZENE DERIVATIVES AND BENZOIC ACID HYPOFLUORITE DERIVATIVES | Fujian Yongjing Technology Co., Ltd. (CN) | 2021-03-03 | — | — | EP | disclosed |
| CN-101535276-B | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC | 2013-08-28 | — | — | CN | disclosed |
| CN-101925578-B | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of ss-secretase (BACE) | JANSSEN PHARMACEUTICA NV | 2012-11-28 | — | — | CN | disclosed |
| CN-101142194-B | Benzazole derivatives, compositions, and methods of use as b-secretase inhibitors | TRANSTECH PHARMA INC | 2012-10-10 | — | — | CN | disclosed |
| CN-101646665-A | 1-(1-benzyl piepridine-4-yl) benzoglyoxaline-5-carboxylic acid derivative that is used for the treatment of diabetes | HOFFMANN LA ROCHE CH | 2010-02-10 | — | — | CN | disclosed |
| CN-101535276-A | 2, 4-diaminopyrimidine fused bicyclic derivatives as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-09-16 | — | — | CN | disclosed |
| CN-101142194-A | Benzazole derivatives, compositions, and methods of use as b-secretase inhibitors | TRANSTECH PHARMA INC (US) | 2008-03-12 | — | — | CN | disclosed |