SCHEMBL23039396

SCHEMBL23039396

CCC(C1CNCCC1CN)N1c2ccccc2Sc2ccc(C(F)(F)F)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 12/20 0.39
TP53 P04637 5/20 0.39
MAPK1 P28482 4/20 0.39
LMNA P02545 4/20 0.39
MAPT P10636 4/20 0.39
CYP1A2 P05177 3/20 0.39
ABCB1 P08183 3/20 0.39
HTR1A P08908 3/20 0.39
ADRA2A P08913 3/20 0.39
ADORA3 P0DMS8 3/20 0.39
CYP2D6 P10635 3/20 0.39
CHRM1 P11229 3/20 0.39
DRD1 P21728 3/20 0.39
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
ADRA1A P35348 3/20 0.39
DRD3 P35462 3/20 0.39
THPO P40225 3/20 0.39
MTOR P42345 3/20 0.39
SLC6A3 Q01959 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23039398 0.76 FPR2 (0.55) FPR2TP53MAPK1LMNAMAPT
SCHEMBL23039399 0.76 SLC6A2 (0.31) LMNACYP1A2HTR1AADRA2ACYP2D6
Hydrochloric Acid SCHEMBL30058873 0.76 FPR2 (0.55) FPR2TP53MAPK1LMNAMAPT
SCHEMBL23954313 0.74 LMNA (0.51) FPR2TP53MAPK1LMNAMAPT
SCHEMBL6672304 0.71 KDM1A (0.38) TP53MAPK1MAPTCYP1A2HTR1A
SCHEMBL17092955 0.66 FPR2 (0.46) FPR2TP53MAPK1LMNAMAPT
SCHEMBL10168444 0.65 FPR2 (0.63) FPR2TP53MAPK1LMNAMAPT
SCHEMBL4320505 0.65 FPR2 (0.47) FPR2TP53MAPK1LMNAMAPT
SCHEMBL20774243 0.64 TP53 (0.67) FPR2TP53MAPK1LMNAMAPT
SCHEMBL21445198 0.64 TP53 (0.67) FPR2TP53MAPK1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542290-B2 Phenothiazine derivatives and uses thereof CAMP4 THERAPEUTICS CORPORATION (US) 2023-01-03 US disclosed
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF CAMP4 THERAPEUTICS CORPORATION 2021-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061837-A1 PHENOTHIAZINE DERIVATIVES AND USES THEREOF RPLP2, RPS2, RPLP1 FPR2 2716/4885TP53 1987/4885MAPK1 3288/4885
US-11542290-B2 Phenothiazine derivatives and uses thereof RPLP2, RPS2, RPLP1 FPR2 2716/4885TP53 1987/4885MAPK1 3288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.