Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23040309 | 1.00 | AOC3 (0.33) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL23040311 | 1.00 | AOC3 (0.33) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL21622780 | 0.91 | AOC3 (0.35) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL23898741 | 0.84 | AOC3 (0.32) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL30018521 | 0.84 | AOC3 (0.32) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL25482504 | 0.84 | AOC3 (0.32) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL25264699 | 0.84 | AOC3 (0.32) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL25264698 | 0.84 | AOC3 (0.32) | AOC3CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL23040305 | 0.83 | HIF1A (0.36) | SLC6A3SLC6A4 | |
| SCHEMBL23040306 | 0.83 | HIF1A (0.36) | SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768659-B1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF ALPHA-(DIARYLMETHYL) ALKYL AMINES | PIRAMAL PHARMA LTD (IN) | 2023-07-19 | — | — | EP | disclosed |
| US-11279668-B2 | Asymmetric synthesis of alpha-(diarylmethyl) alkyl amines | PIRAMAL PHARMA LIMITED (IN) | 2022-03-22 | — | — | US | disclosed |
| US-20210061752-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-(DIARYLMETHYL) ALKYL AMINES | Piramal Enterprises Limited (IN) | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210061752-A1 | AN IMPROVED ASYMMETRIC SYNTHESIS OF alpha-(DIARYLMETHYL) ALKYL AMINES | SAT1, BET1, SRM | AOC3 1779/4885CACNA1F 331/4885CHRM2 1454/4885 |
| US-11279668-B2 | Asymmetric synthesis of alpha-(diarylmethyl) alkyl amines | SAT1, SRM, SMS | AOC3 1433/4885CACNA1F 428/4885CHRM2 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.