SCHEMBL23040313

SCHEMBL23040313

O=C(O)CCCCCCC(=O)Nn1ccc(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DUT P33316 6/20 0.45
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
NAAA Q02083 1/20 0.38
PTGS1 P23219 4/20 0.37
PTGS2 P35354 4/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598528 0.76 NAAA (0.61) DUTNAAA
SCHEMBL13539818 0.74 NAAA (0.59) DUTNAAA
SCHEMBL2181554 0.64 CRBN (0.54) DUTALDH1A1LMNACA1CA2
SCHEMBL25367953 0.64 NAAA (0.45) DUTALDH1A1LMNANAAA
SCHEMBL25430771 0.64 GPR84 (0.44)
Sebacic Acid SCHEMBL30166507 0.62 TSHR (0.92) ALDH1A1LMNA
SCHEMBL31211775 0.62 TSHR (0.92) ALDH1A1LMNA
Sebacic Acid SCHEMBL27937400 0.60 TSHR (0.86) ALDH1A1LMNA
SCHEMBL25186232 0.59 TSHR (1.00) ALDH1A1LMNA
Azelaic Acid SCHEMBL2724296 0.59 TSHR (1.00) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11479534-B2 Compound and use thereof in medicine CHANGSHA HOOZ BIOSCIENCE AND TECHNOLOGY CO., LTD (CN) 2022-10-25 US disclosed
US-20210061773-A1 COMPOUND AND USE THEREOF IN MEDICINE CHANGSHA HOOZ BIOSCIENCE AND TECHNOLOGY CO., LTD (CN) 2021-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061773-A1 COMPOUND AND USE THEREOF IN MEDICINE HDAC1, HDAC11, HDAC10 DUT 2793/4885ALDH1A1 269/4885LMNA 4364/4885
US-11479534-B2 Compound and use thereof in medicine HDAC1, HDAC11, HDAC10 DUT 2793/4885ALDH1A1 269/4885LMNA 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.