Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692045 | 1.00 | CYP4F2 (0.51) | CYP4F2CYP4A11ACHEHSP90AA1LOXL2 | |
| SCHEMBL17978223 | 0.85 | ABCB1 (0.54) | CYP4F2CYP4A11HDAC1NPC1RAB9A | |
| SCHEMBL5365504 | 0.79 | HSP90AA1 (0.53) | HSP90AA1PLA2G2APTGER4MAOBALDH1A1 | |
| SCHEMBL23040963 | 0.79 | RXRA (0.51) | ALDH1A1HPGDMRGPRX4HDAC1TAAR1 | |
| SCHEMBL30186713 | 0.79 | RXRA (0.52) | MAOBCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL24926716 | 0.79 | RXRA (0.52) | MAOBCYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7241172 | 0.77 | CCR6 (0.53) | CYP4F2CYP4A11LOXL2PLA2G2AALDH1A1 | |
| SCHEMBL70173 | 0.75 | CYP4F2 (0.83) | CYP4F2CYP4A11LOXL2ALDH1A1HPGD | |
| SCHEMBL5724917 | 0.75 | CYP4F2 (0.63) | CYP4F2CYP4A11LOXL2TRPV1ALDH1A1 | |
| SCHEMBL8993207 | 0.75 | PTGER4 (0.55) | CYP4F2CYP4A11HSP90AA1LOXL2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186881-A1 | P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2023-10-05 | — | — | WO | disclosed |
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| WO-2021038292-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| WO-2021038292-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | MAPK1, MAPK8, MAPK7 | CYP4F2 2652/4885CYP4A11 602/4885ACHE 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.