Phosphonic Acid

Phosphonic Acid

SCHEMBL23041004

C1=Cc2ccc3cc[se]c3c2OC1.O=[PH](O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21404604 0.91 CYP1A1 (0.34) CYP1A1CYP1A2
SCHEMBL30602816 0.69 CYP1A1 (0.34) CYP1A1CYP1A2
SCHEMBL29372595 0.62 CYP2B6 (0.43) CYP1A1CYP1A2
SCHEMBL29365059 0.62 CYP2B6 (0.43) CYP1A1CYP1A2
Phosphonic Acid SCHEMBL3258285 0.62 CYP2B6 (0.40) CYP1A1CYP1A2
SCHEMBL28185909 0.61 MET (0.40) CYP1A1CYP1A2
SCHEMBL9099368 0.61 CYP1A1 (0.38) CYP1A1CYP1A2
SCHEMBL9105068 0.60 CYP1A1 (0.34) CYP1A1CYP1A2
SCHEMBL29609339 0.60 CYP1A1 (0.34) CYP1A1CYP1A2
SCHEMBL3708936 0.59 HPRT1 (0.47) CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021038306-A1 SELENOPHENOCHROMENE PHOSPHONIC ACIDS, PREPARATION AND USE AS ANTIPROLIFERATIVE AGENTS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2021-03-04 WO disclosed