Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL23041004 | 0.91 | CYP1A1 (0.33) | CYP1A1CYP1A2 | |
| SCHEMBL30602816 | 0.76 | CYP1A1 (0.34) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL29372595 | 0.68 | CYP2B6 (0.43) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL29365059 | 0.68 | CYP2B6 (0.43) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL1043402 | 0.68 | CYP2B6 (0.43) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL9099368 | 0.67 | CYP1A1 (0.38) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL9105068 | 0.66 | CYP1A1 (0.34) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL29609339 | 0.66 | CYP1A1 (0.34) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL3708936 | 0.64 | HPRT1 (0.47) | CYP1A1CYP1A2CYP2B6 | |
| SCHEMBL3703014 | 0.64 | CYP1A2 (0.45) | CYP1A1CYP1A2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612417-B2 | Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2026-04-28 | — | — | US | disclosed |
| EP-3849988-B1 | SELENOPHENOCHROMENE HYDROXAMIC ACIDS, PREPARATION AND USE AS ANGIOGENESIS INHIBITORS | LATVIAN INST ORGANIC SYNTHESIS (LV) | 2023-10-11 | — | — | EP | disclosed |
| US-20230002411-A1 | Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2023-01-05 | — | — | US | disclosed |
| US-20210403486-A1 | SELENOPHENOCHROMENE HYDROXAMIC ACIDS, PREPARATION AND USE AS ANGIOGENESIS INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-12-30 | — | — | US | disclosed |
| EP-3849988-A1 | SELENOPHENOCHROMENE HYDROXAMIC ACIDS, PREPARATION AND USE AS ANGIOGENESIS INHIBITORS | Latvian Institute Of Organic Synthesis (LV) | 2021-07-21 | — | — | EP | disclosed |
| WO-2021123928-A1 | DEUTERATED ANALOGUES OF SELENOPHENOCHROMENES, SYNTHESIS THEREOF, AND METHODS OF USING SAME AGENTS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021038306-A1 | SELENOPHENOCHROMENE PHOSPHONIC ACIDS, PREPARATION AND USE AS ANTIPROLIFERATIVE AGENTS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2021-03-04 | — | — | WO | disclosed |
| EP-3487859-B1 | ANTIMETASTATIC 2H-SELENOPHENO[3,2-H]CHROMENES, SYNTHESIS THEREOF, AND METHODS OF USING SAME AGENTS | LATVIAN INST ORGANIC SYNTHESIS (LV) | 2021-01-20 | — | — | EP | disclosed |
| WO-2020053639-A1 | SELENOPHENOCHROMENE HYDROXAMIC ACIDS, PREPARATION AND USE AS ANGIOGENESIS INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2020-03-19 | — | — | WO | disclosed |
| US-10561681-B2 | Antimetastatic 2H-selenopheno[3,2-h]chromenes, synthesis thereof, and methods of using same agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2020-02-18 | — | — | US | disclosed |
| US-10561681-B2 | Antimetastatic 2H-selenopheno[3,2-h]chromenes, synthesis thereof, and methods of using same agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2020-02-18 | — | — | US | disclosed |
| US-20190298758-A1 | Antimetastatic 2H-Selenopheno[3,2-h]chromenes, Synthesis Thereof, and Methods of Using Same Agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2019-10-03 | — | — | US | disclosed |
| US-20190298758-A1 | Antimetastatic 2H-Selenopheno[3,2-h]chromenes, Synthesis Thereof, and Methods of Using Same Agents | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190298758-A1 | Antimetastatic 2H-Selenopheno[3,2-h]chromenes, Synthesis Thereof, and Methods of Using Same Agents | SELENOI, GPX1, GPX4 | CYP1A1 1342/4885CYP1A2 1086/4885CYP2B6 857/4885 |
| US-20230002411-A1 | Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents | HCCS, DHPS, SCLY | CYP1A1 221/4885CYP1A2 214/4885CYP2B6 196/4885 |
| US-20210403486-A1 | SELENOPHENOCHROMENE HYDROXAMIC ACIDS, PREPARATION AND USE AS ANGIOGENESIS INHIBITORS | EDF1, VEGFA, HDGF | CYP1A1 2395/4885CYP1A2 1188/4885CYP2B6 1370/4885 |
| US-10561681-B2 | Antimetastatic 2H-selenopheno[3,2-h]chromenes, synthesis thereof, and methods of using same agents | SELENOI, GPX1, GPX4 | CYP1A1 1342/4885CYP1A2 1086/4885CYP2B6 857/4885 |
| US-12612417-B2 | Deuterated analogues of selenophenochromenes, synthesis thereof, and methods of using same agents | HCCS, GPX1, CRY1 | CYP1A1 313/4885CYP1A2 244/4885CYP2B6 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.