Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA9 | Q16790 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 13/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708140 | 0.97 | CA1 (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL29510961 | 0.97 | CA1 (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL26977490 | 0.94 | CA1 (0.44) | CA1CA2CA9CA12CA14 | |
| SCHEMBL26978097 | 0.94 | LGALS3 (0.44) | CA1CA2CA9CA12CA14 | |
| SCHEMBL26977569 | 0.91 | CA1 (0.43) | CA1CA2CA9CA12CA14 | |
| SCHEMBL28755721 | 0.90 | LGALS3 (0.42) | LGALS3 | |
| SCHEMBL29510953 | 0.89 | CA1 (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL29511012 | 0.87 | CA1 (0.46) | CA1CA2CA9CA12CA14 | |
| SCHEMBL23950966 | 0.87 | CA1 (0.47) | CA1CA2CA9CA12CA14 | |
| SCHEMBL22981049 | 0.87 | CA1 (0.47) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250257056-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-08-14 | — | — | US | disclosed |
| US-12319672-B2 | Alpha-D-galactopyranoside derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-03 | — | — | US | disclosed |
| US-12312362-B2 | Spiro derivatives of Alpha-D-galactopyranosides | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-27 | — | — | US | disclosed |
| EP-4225752-B1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-12-11 | — | — | EP | disclosed |
| EP-4021904-B1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-03 | — | — | EP | disclosed |
| US-20230295182-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-09-21 | — | — | US | disclosed |
| EP-4225752-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | Idorsia Pharmaceuticals Ltd (CH) | 2023-08-16 | — | — | EP | disclosed |
| US-20220281855-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-08 | — | — | US | disclosed |
| EP-4021904-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-07-06 | — | — | EP | disclosed |
| WO-2022073969-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-04-14 | — | — | WO | disclosed |
| WO-2021038068-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257056-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | LGALS1, LGALS3, LGALS2 | CA1 2514/4885CA2 1967/4885CA9 1535/4885 |
| US-20220281855-A1 | ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES | LGALS1, LGALS3, LGALS2 | CA1 1135/4885CA2 777/4885CA9 471/4885 |
| US-12312362-B2 | Spiro derivatives of Alpha-D-galactopyranosides | LGALS1, LGALS3, LGALS2 | CA1 2222/4885CA2 2225/4885CA9 1581/4885 |
| US-12319672-B2 | Alpha-D-galactopyranoside derivatives | LGALS1, LGALS3, LGALS2 | CA1 1135/4885CA2 777/4885CA9 471/4885 |
| US-20230295182-A1 | SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES | LGALS1, LGALS3, LGALS2 | CA1 2222/4885CA2 2225/4885CA9 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.