Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.97 |
| ▸ | THRB | P10828 | 1/20 | 0.97 |
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metronidazole SCHEMBL9482744 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL31108924 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL23042 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL5313560 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL2221140 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL9481347 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL9455119 | 0.98 | LMNA (1.00) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL5595814 | 0.97 | LMNA (0.97) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL8667859 | 0.97 | LMNA (0.97) | LMNAALDH1A1MAPK1THRBTSHR | |
| Metronidazole SCHEMBL8675069 | 0.97 | LMNA (0.97) | LMNAALDH1A1MAPK1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014027006-A1 | BIOADHESIVE FORMULATIONS FOR USE IN DRUG DELIVERY | EDKO PAZARLAMA TANITIM TICARET LIMITED SIRKETI (TR) | 2014-02-20 | — | — | WO | disclosed |
| US-7763164-B1 | Gasoline sulfur reduction in FCCU cracking | MARATHON PETROLEUM COMPANY LLC (US) | 2010-07-27 | — | — | US | disclosed |
| US-5800797-A | USED FOR CATALYST SUPPORT OR ADSORBENT | CATALYSTS & CHEMICALS INDUSTRIES CO., LTD. (JP) | 1998-09-01 | — | — | US | disclosed |