SCHEMBL2304233

SCHEMBL2304233

CCOP(=O)(Cc1c(C)cc(C)cc1C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AOX1 Q06278 1/20 0.50
ACHE P22303 1/20 0.43
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
CCNT1 O60563 2/20 0.37
CDK9 P50750 2/20 0.37
POLB P06746 1/20 0.36
HTT P42858 1/20 0.36
HIF1A Q16665 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363978 0.81 MEN1 (0.37) AOX1ACHEMEN1KMT2ASMN1; SMN2
SCHEMBL28996290 0.79 AOX1 (0.40) AOX1ACHEMEN1KMT2ASMN1; SMN2
SCHEMBL4922540 0.78 MEN1 (0.43) AOX1ACHEMEN1KMT2ASMN1; SMN2
SCHEMBL18317179 0.78 AOX1 (0.49) AOX1ACHEMEN1KMT2ANPSR1
SCHEMBL35192 0.77 HTT (0.53) MEN1KMT2ANPSR1L3MBTL1ALDH1A1
SCHEMBL1326156 0.77 HTT (0.41) MEN1KMT2ANPSR1ALDH1A1HTT
SCHEMBL7916451 0.77 AOX1 (0.58) AOX1ACHEMEN1KMT2ANPSR1
SCHEMBL18955117 0.76 HTT (0.39) MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL28775854 0.76 MEN1 (0.41) AOX1ACHEMEN1KMT2ASMN1; SMN2
SCHEMBL19008528 0.76 CFTR (0.52) MEN1KMT2AALDH1A1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588159-B1 Process for preparing alpha-carbonyl-phospine oxides BASF AG (DE) 1998-07-29 EP claimed
CN-112673035-B Composite material comprising ceramic fibers and nanoclusters, dental product, kit and method of making and using the same 舒万诺知识产权公司 2024-04-19 CN disclosed
CN-110819249-B Back grinding belt 日东电工株式会社 2024-03-01 CN disclosed
CN-113164328-B Difunctional and multifunctional coinitiators in dental compositions 登士柏德特里有限公司 2024-02-27 CN disclosed
CN-113099718-B Imidazole/thiol polymerization initiation system 登士柏希罗纳有限公司 2024-02-13 CN disclosed
CN-117447936-A Pressure-sensitive adhesive sheet for semiconductor processing 日东电工株式会社 2024-01-26 CN disclosed
CN-117447937-A Pressure-sensitive adhesive sheet for semiconductor processing 日东电工株式会社 2024-01-26 CN disclosed
CN-112135598-B Macromer-based photocurable dental impression material 登士柏希罗纳有限公司 2023-12-22 CN disclosed
CN-117070160-A Adhesive tape for semiconductor processing 日东电工株式会社 2023-11-17 CN disclosed
CN-112839981-B dental composition 登士柏德特里有限公司 2023-11-17 CN disclosed
US-8357397-B2 Controlled release composition comprising a recombinant gelatin FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2013-01-22 US disclosed
CN-101610749-B Dental filler and methods 3M INNOVATIVE PROPERTIES CO 2013-01-02 CN disclosed
CN-102781921-A Compositions and articles comprising polymerizable ionic liquid mixtures and methods of curing 3M INNOVATIVE PROPERTIES CO 2012-11-14 CN disclosed
CN-101557772-B Dental articles, methods, and kits including a compressible material 3M INNOVATIVE PROPERTIES CO 2012-10-10 CN disclosed
EP-2349993-A1 SULFONIUM DERIVATIVES AND THE USE THEROF AS LATENT ACIDS BASF SE (DE) 2011-08-03 EP disclosed
CN-101808981-A Methacrylate based monomers containing a urethane linkage, process for production and use thereof 3M INNOVATIVE PROPERTIES CO 2010-08-18 CN disclosed
US-20100203138-A1 Controlled Release Composition Comprising a Recombinant Gelatin FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2010-08-12 US disclosed
WO-2010046240-A1 SULFONIUM DERIVATIVES AND THE USE THEROF AS LATENT ACIDS BASF SE (DE) 2010-04-29 WO disclosed
CN-101610749-A Dental filler and method 3M INNOVATIVE PROPERTIES CO (US) 2009-12-23 CN disclosed
US-5026742-A Containing dihydroxy (meth)acrylate and tertiary amine compound BASF AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed