Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 12/20 | 0.61 |
| ▸ | MAP4K2 | Q12851 | 12/20 | 0.61 |
| ▸ | LCK | P06239 | 7/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | BMX | P51813 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 1/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045832 | 0.86 | TNK2 (0.59) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL19922951 | 0.85 | TNK2 (0.67) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL23045858 | 0.84 | TNK2 (0.82) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL23045876 | 0.80 | TNK2 (0.80) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL19922745 | 0.77 | TNK2 (0.84) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL19865443 | 0.76 | TNK2 (0.72) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL23059372 | 0.76 | TNK2 (0.79) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL23039234 | 0.75 | LCK (1.00) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL19922758 | 0.75 | TNK2 (0.78) | TNK2MAP4K2LCKABL1BMX | |
| SCHEMBL19922743 | 0.75 | TNK2 (0.73) | TNK2MAP4K2LCKABL1BMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021040422-A1 | NOVEL PYRIMIDO[4,5-D]PYRIMIDINE-2-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY | 한국과학기술연구원 | 2021-03-04 | — | — | WO | disclosed |