Methylpyrrolidone

Methylpyrrolidone

SCHEMBL2304675

CCN(C=O)CC.CN(C)C=O.CN1CCCC1=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.55
BRD2 P25440 1/20 0.55
TSHR P16473 1/20 0.39
MEN1 O00255 3/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
IDE P14735 1/20 0.33
PARP1 P09874 2/20 0.33
PIK3CD O00329 1/20 0.32
PSMD14 O00487 2/20 0.31
GAA P10253 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL6937992 0.95 BRD4 (0.61) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL22765 0.88 BRD4 (0.71) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL19124976 0.80 BRD4 (0.59) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL27412413 0.80 BRD4 (0.59) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL9782937 0.80 BRD4 (0.59) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL10422809 0.79 BRD4 (0.57) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL28029619 0.79 BRD4 (0.57) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL10574753 0.79 BRD4 (0.57) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL10934000 0.77 BRD4 (0.55) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL6886896 0.77 BRD4 (0.71) BRD4BRD2TSHRMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8886106-B2 Intermediate transfer belt and method for producing the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2014-11-11 US disclosed
US-8470232-B2 Annular belt made of polyimide and a production method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-06-25 US disclosed
US-20120225376-A1 INTERMEDIATE TRANSFER BELT AND METHOD FOR PRODUCING THE SAME KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-09-06 US disclosed
US-20110196124-A1 ANNULAR BELT MADE OF POLYIMIDE AND A PRODUCTION METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-08-11 US disclosed