Methylpyrrolidone

Methylpyrrolidone

SCHEMBL22765

CN(C)C=O.CN1CCCC1=O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.71
BRD2 P25440 1/20 0.71
TSHR P16473 2/20 0.42
INMT O95050 2/20 0.37
MEN1 O00255 5/20 0.37
MAPT P10636 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 4/20 0.37
ALDH1A1 P00352 4/20 0.37
RAB9A P51151 3/20 0.37
PSMD14 O00487 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.35
PIK3CD O00329 1/20 0.34
IDE P14735 2/20 0.34
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL9782937 0.91 BRD4 (0.59) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL27412413 0.91 BRD4 (0.59) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL19124976 0.91 BRD4 (0.59) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL28029619 0.89 BRD4 (0.57) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL10574753 0.89 BRD4 (0.57) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL10422809 0.89 BRD4 (0.57) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL10934000 0.88 BRD4 (0.55) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL2304675 0.88 BRD4 (0.55) BRD4BRD2TSHRMEN1MAPT
Methylpyrrolidone SCHEMBL11078812 0.87 BRD4 (0.85) BRD4BRD2TSHRINMTMEN1
Methylpyrrolidone SCHEMBL20720688 0.85 BRD4 (0.81) BRD4BRD2TSHRINMTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2600198-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING PHTHALOCYANINE CRYSTAL, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND PHTHALOCYANINE CRYSTAL CANON KK (JP) 2017-03-08 EP claimed
EP-2486175-B1 A PROCESS OF MANUFACTURING LOW FIBRILLATING CELLULOSE FIBERS GRASIM IND LTD (IN) 2015-05-20 EP claimed
US-8952146-B2 Process for manufacturing low-fibrillating cellulosic fiber GRASIM INDUSTRIES LIMITED (IN) 2015-02-10 US claimed
US-20120253031-A1 PROCESS FOR MANUFACTURING LOW-FIBRILLATING CELLULOSIC FIBER GRASIM INDUSTRIES LIMITED (IN) 2012-10-04 US claimed
WO-2012114349-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PENTOSAN POLYSULFATE SODIUM CADILA HEALTHCARE LIMITED (IN) 2012-08-30 WO claimed
US-7728082-B2 Methods for preparing polymers from phenolic materials and compositions relating thereto DUPONT ELECTRONIC POLYMERS L.P. (US) 2010-06-01 US claimed
US-20090247791-A1 PROCESS FOR THE PREPARATION OF FLUOROMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL) ETHYL ETHER CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) 2009-10-01 US claimed
US-7227017-B2 Process for the preparation of phosphorothioate oligonucleotides AVECIA LIMITED (GB) 2007-06-05 US claimed
US-6054554-A HEAT RESISTANT; RADIATION TRANSPARENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2000-04-25 US claimed
EP-0581886-B1 METHOD OF PROCESSING NEUTRAL POLYANILINES IN SOLVENT AND SOLVENT MIXTURES ZIPPERLING KESSLER & CO (DE) 1999-03-10 EP claimed
US-4644033-A CROSSLINKING OF POLYISOCYANATE AND POLYOXYETHYLENE IN NONAQUEOUS SOLVENT ESSILOR INTERNATIONAL (FR) 1987-02-17 US claimed
US-4545818-A WETTING AGENT, COLORING AGENT, XANTHAN GUM, AND PERMEABLE SOLVENT UNITED KINGDOM ATOMIC ENERGY AUTHORITY (GB) 1985-10-08 US claimed
US-4544705-A MOLDING MATERIALS, ADHESIVES UNION CARBIDE CORPORATION (US) 1985-10-01 US claimed
US-20240157304-A1 SPACER FOR A SPIRAL WOUND MEMBRANE EVOVE LTD (GB) 2024-05-16 US disclosed
US-20240149223-A1 MEMBRANE DEVICE EVOVE LTD (GB) 2024-05-09 US disclosed
CN-117860718-A Amantadine compositions, methods of making and using the same 阿达玛斯药物有限责任公司 2024-04-12 CN disclosed
US-4240941-A Coating compositions GENERAL ELECTRIC COMPANY (US) 1980-12-23 US disclosed
EP-0019728-A1 Utilisation of reactive dyestuffs in dyeing and printing blended fabrics polyester/cotton BAYER AG (DE) 1980-12-10 EP disclosed
US-4163850-A BACTERICIDES FOR WATER TREATMENT PETROLITE CORPORATION (US) 1979-08-07 US disclosed
US-4101654-A BACTERIAL GROWTH INHIBITION PETROLITE CORPORATION (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247791-A1 PROCESS FOR THE PREPARATION OF FLUOROMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL) ETHYL ETHER CA3, PFAS, PFDN2 BRD4 4614/4885BRD2 3751/4885TSHR 822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.