Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | BRD2 | P25440 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | IDE | P14735 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpyrrolidone SCHEMBL2304675 | 0.95 | BRD4 (0.55) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL8151260 | 0.81 | BRD4 (0.71) | BRD4BRD2KMT2AMEN1MAPT | |
| Methylpyrrolidone SCHEMBL22765 | 0.81 | BRD4 (0.71) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL6886896 | 0.81 | BRD4 (0.71) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL10902634 | 0.80 | BRD4 (0.85) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL28122179 | 0.80 | — | — | |
| Methylpyrrolidone SCHEMBL28963630 | 0.79 | BRD4 (0.68) | BRD4BRD2KMT2AMEN1MAPT | |
| Methylpyrrolidone SCHEMBL3306767 | 0.79 | BRD4 (0.68) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL20720688 | 0.78 | BRD4 (0.81) | BRD4BRD2TSHRKMT2AMEN1 | |
| Methylpyrrolidone SCHEMBL7540126 | 0.78 | BRD4 (0.81) | BRD4BRD2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230229-B1 | METHOD FOR PRODUCING 2-CHLORO-5-CHLOROMETHYL-1,3-THIAZOL | DSM FINE CHEM AUSTRIA GMBH (AT) | 2003-05-28 | — | — | EP | disclosed |
| US-5059220-A | COMPOSITE POLYMERIC MEMBRANES FOR THE SEPARATION OF MIXTURES OF GASES AND THE METHOD OF PREPARATION THE SAME | CESKOSLOVENSKA AKADEMIE VED (CS) | 1991-10-22 | — | — | US | disclosed |