Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | TGM1 | P22735 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741353 | 0.90 | WNT3A (0.57) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL29020664 | 0.88 | WNT3A (0.58) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30385839 | 0.88 | WNT3A (0.58) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28907538 | 0.88 | WNT3A (0.63) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL22812969 | 0.88 | WNT3A (0.55) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4065096 | 0.87 | WNT3A (0.55) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24483274 | 0.86 | WNT3A (0.57) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4069752 | 0.86 | WNT3A (0.58) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL18661912 | 0.86 | WNT3A (0.54) | WNT3ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL17675597 | 0.85 | WNT3A (0.62) | WNT3ASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786160-A1 | PYRIDINE DERIVATIVES AND THERAPEUTIC USES THEREOF AS TRPC6 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2021-03-03 | — | — | EP | disclosed |