Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | TGM1 | P22735 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020664 | 1.00 | WNT3A (0.58) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24483274 | 0.89 | WNT3A (0.57) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28907538 | 0.88 | WNT3A (0.63) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23047380 | 0.88 | WNT3A (0.57) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4069752 | 0.86 | WNT3A (0.58) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6741353 | 0.86 | WNT3A (0.57) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL17675597 | 0.85 | WNT3A (0.62) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22812969 | 0.84 | WNT3A (0.55) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4065096 | 0.83 | WNT3A (0.55) | WNT3AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30385836 | 0.83 | WNT3A (0.55) | WNT3AMAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919859-B | Pharmaceutical composition of heteroaryl derivative and application of pharmaceutical composition in medicine | 四川海思科制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-115919859-A | Pharmaceutical composition of heteroaryl derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-07 | — | — | CN | disclosed |