Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | CTSK | P43235 | 4/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSC | P53634 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR7 | P34969 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DCK | P27707 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688099 | 0.89 | CTSL (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL266924 | 0.86 | HTT (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL31163204 | 0.86 | HTT (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL3409484 | 0.86 | CTSL (0.61) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL738542 | 0.85 | HTT (0.67) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL3712567 | 0.83 | CTSL (0.53) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL3917510 | 0.81 | HTT (0.71) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL18343804 | 0.81 | KDM4E (0.56) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL29812078 | 0.79 | MCHR1 (0.55) | ALDH1A1LMNAMAPK1BRD4MAPT | |
| SCHEMBL23052298 | 0.79 | CTSL (0.64) | CTSLCTSKCTSSCTSCCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786156-A1 | 10H-PHENOTHIAZINE FERROPTOSIS INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Chengdu Henghao Investment Co. Limited (CN) | 2021-03-03 | — | — | EP | disclosed |