Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.64 |
| ▸ | CTSK | P43235 | 4/20 | 0.64 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CTSC | P53634 | 3/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 8/20 | 0.60 |
| ▸ | HTR7 | P34969 | 8/20 | 0.60 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | DCK | P27707 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688099 | 0.85 | CTSL (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL23052557 | 0.84 | DRD2 (0.61) | HTR1AHTR7DRD2ADRA1DADRA1A | |
| SCHEMBL23052382 | 0.83 | HTT (0.65) | CTSLCTSKHTR1AHTR7DCK | |
| SCHEMBL266924 | 0.83 | HTT (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL31163204 | 0.83 | HTT (0.64) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL3409484 | 0.83 | CTSL (0.61) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL17907549 | 0.82 | CTSL (0.61) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL738542 | 0.81 | HTT (0.67) | CTSLCTSKCTSSCTSCCTSB | |
| SCHEMBL23052553 | 0.79 | ALDH1A1 (0.53) | DRD2ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL23048255 | 0.79 | CTSL (0.57) | CTSLCTSKCTSSCTSCCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021039824-A1 | RNA METHYLTRANSFERASE INHIBITOR, SCREENING METHOD THEREFOR, ANTI-CANCER AGENT EFFICACY ASSESSMENT MARKER, AND KIT FOR EFFECTIVELY PREDICTING FTSJ1 INHIBITOR | 国立大学法人 岡山大学 | 2021-03-04 | — | — | WO | disclosed |