Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528932 | 0.79 | CYP4F2 (0.63) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL13626610 | 0.79 | MAOB (0.62) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL22883006 | 0.78 | CYP4F2 (0.57) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL1268719 | 0.77 | MAOB (0.81) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL30344886 | 0.76 | MAOB (0.69) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL1636426 | 0.76 | BCHE (0.58) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL538272 | 0.76 | MAOB (0.69) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL15761340 | 0.74 | BCHE (0.70) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| Benzylphenylether SCHEMBL27762453 | 0.74 | MAOB (0.71) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL8042202 | 0.73 | MAOB (0.58) | CYP4F2CYP4A11MAOBNR4A2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786156-A1 | 10H-PHENOTHIAZINE FERROPTOSIS INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Chengdu Henghao Investment Co. Limited (CN) | 2021-03-03 | — | — | EP | disclosed |