Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.63 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626610 | 0.83 | MAOB (0.62) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL22883006 | 0.81 | CYP4F2 (0.57) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL1268719 | 0.81 | MAOB (0.81) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL20610916 | 0.80 | CYP1A2 (0.66) | MAOBNR4A2BCHEMAOAALOX5 | |
| SCHEMBL15425251 | 0.79 | CYP4F2 (0.63) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| Benzylphenylether SCHEMBL22314 | 0.79 | LMNA (0.69) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL23048269 | 0.79 | CYP4F2 (0.54) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL29548398 | 0.78 | APP (0.71) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL384725 | 0.78 | APP (0.71) | CYP4F2CYP4A11MAOBNR4A2BCHE | |
| SCHEMBL15761340 | 0.77 | BCHE (0.70) | CYP4F2CYP4A11MAOBNR4A2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181014-B1 | HETEROCYCLIC CONTAINING BIPHENYL aP2 INHIBITORS AND METHOD | BRISTOL MYERS SQUIBB CO (US) | 2007-05-23 | — | — | EP | disclosed |