Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27037987 | 0.88 | MAOB (0.66) | MAOBGUSBNR4A2BCHEMAOA | |
| SCHEMBL11764164 | 0.86 | GAA (0.50) | MEN1KMT2A | |
| SCHEMBL17361545 | 0.83 | KDM4E (0.50) | MAOBMEN1KMT2A | |
| SCHEMBL1268719 | 0.82 | MAOB (0.81) | MAOBNR4A2CYP4F2CYP4A11BCHE | |
| SCHEMBL7281686 | 0.81 | CYP4F2 (0.60) | MAOBGUSBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL38671 | 0.80 | KCNA3 (0.58) | — | |
| SCHEMBL30344886 | 0.80 | MAOB (0.69) | MAOBNR4A2CYP4F2CYP4A11BCHE | |
| SCHEMBL538272 | 0.80 | MAOB (0.69) | MAOBNR4A2CYP4F2CYP4A11BCHE | |
| SCHEMBL1636426 | 0.80 | BCHE (0.58) | MAOBGUSBNR4A2CYP4F2CYP4A11 | |
| SCHEMBL16502341 | 0.79 | ALDH1A1 (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051605-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA USING A COMPOUND THAT IS AN ANTAGONIST OF DOPAMINE D4 RECEPTORS | WARNER-LAMBERT COMPANY (US) | 2000-04-18 | — | — | US | disclosed |