Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.69 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 2/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559921 | 0.90 | ADRB2 (0.74) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| SCHEMBL7271885 | 0.83 | ADRB2 (0.80) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| SCHEMBL23931055 | 0.82 | ADRB2 (0.64) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| Salmeterol SCHEMBL4767 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| Salmeterol SCHEMBL4768 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| Salmeterol SCHEMBL4452108 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| Salmeterol SCHEMBL29397921 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| Salmeterol SCHEMBL29393289 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| SCHEMBL4450046 | 0.81 | ADRB2 (1.00) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 | |
| SCHEMBL22035288 | 0.81 | ADRB2 (0.69) | ADRB2ADRB1ADRB3ADRA2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054920-B1 | DRY POWDER INHALER | TEVA BRANDED PHARMACEUTICAL PRODUCTS R&D INC (US) | 2021-03-03 | — | — | EP | disclosed |