Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23048781 | 0.82 | MAP3K5 (0.39) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23865458 | 0.82 | MAP3K5 (0.36) | SLC6A4 | |
| SCHEMBL23865352 | 0.81 | HCRTR1 (0.30) | — | |
| SCHEMBL30809618 | 0.73 | SLC6A4 (0.48) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27090021 | 0.73 | SLC6A4 (0.48) | KDM1AHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23048746 | 0.72 | MAP3K5 (0.31) | — | |
| SCHEMBL23048795 | 0.72 | RAB9A (0.36) | — | |
| SCHEMBL23048617 | 0.70 | — | — | |
| SCHEMBL416139 | 0.68 | KDM1A (0.48) | KDM1AHTR1APTGER1S1PR5 | |
| SCHEMBL22473952 | 0.68 | MAP3K5 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572401-B1 | ASK1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |
| EP-3572412-B1 | PYRIDINE DERIVATIVE AS ASK1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-03-03 | — | — | EP | disclosed |