Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23865352 | 0.81 | HCRTR1 (0.30) | — | |
| SCHEMBL23865466 | 0.78 | MAP3K5 (0.44) | MAP3K5 | |
| SCHEMBL23048795 | 0.76 | RAB9A (0.36) | MAP3K5 | |
| SCHEMBL23865458 | 0.76 | MAP3K5 (0.36) | MAP3K5 | |
| SCHEMBL23048780 | 0.72 | KDM1A (0.37) | — | |
| SCHEMBL29977623 | 0.68 | RORC (0.37) | MAP3K5 | |
| SCHEMBL15135998 | 0.68 | RORC (0.37) | MAP3K5 | |
| SCHEMBL28602065 | 0.67 | — | — | |
| SCHEMBL21155474 | 0.65 | — | — | |
| SCHEMBL28380967 | 0.64 | PDE4D (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572412-B1 | PYRIDINE DERIVATIVE AS ASK1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2021-03-03 | — | — | EP | disclosed |